WebJan 10, 2008 · CD47, originally named integrin-associated protein, is a receptor for thrombospondin-1. ... (or TSP2). 21 Earlier studies using TSP1 antibodies 82,83 and … WebAuthor SummaryFig. P1.(A and B) Nitric oxide-TSP2 axis modulates tissue repair. ... (22, 23) through interactions with CD36 and CD47 during ischemia. TSP1 has also been described to diminish eNOS activity by blocking phosphorylation at S1176 . Studies in retina angiogenesis connected oxidative stress and regulation of TSP2.
方兴未艾 - 免疫疗法新靶点CD47浅析 - 知乎 - 知乎专栏
WebFeb 27, 2024 · TSP1 and TSP2 have the ability to bind to the CD47 receptor, determining an important role in the control of apoptosis and programmed cell death in inflammatory … WebThe weak activity of TSP2 to inhibit NO/cGMP signaling via CD47 may explain why TSP2-null animals respond so poorly to ischemic challenge. Strain-specific characteristics may … fish illness symptoms
Thrombospondin-1 CD47 Signalling: From Mechanisms to Medicine
WebMar 21, 2024 · Ligand for CD36 mediating antiangiogenic properties. ( TSP2_HUMAN,P35442) Gene Wiki entry for THBS2 Gene. Additional gene information for … WebBackground CD47 checkpoint inhibition has yielded promising results in clinical trials, particularly when combined with other immunotherapeutics. Therefore, we here combined … WebFeb 29, 2024 · PDF On Feb 29, 2024, A. Petrov published TSP1,TSP2 and CD47 Find, read and cite all the research you need on ResearchGate can a uk citizen live in sweden