WebFeb 11, 2024 · Phenotypically modulated smooth muscle cells (SMCs) contribute to atherosclerosis in women. How these phenotypically modulated SMCs shape female … WebNov 8, 2024 · The root system architecture (RSA) of plants is highly dependent on the surrounding nutrient environment. The uptake of essential nutrients triggers various signaling cascades and fluctuations in plant hormones to elicit physical changes in RSA. These pathways may involve signaling components known as small signaling peptides …
Potential Contribution of Phenotypically Modulated …
WebAug 1, 2024 · In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate, proliferate and migrate in a process known as phenotypic modulation. However, the phenotype of... WebNov 11, 2024 · In-depth single-cell RNA sequencing demonstrates that SMC-Has3 deletion driven expansion of phenotypically modulated SMC drives increases in acute-phase response gene expression. Blocking the important HA binding receptor, cluster of differentiation-44 (CD44), recapitulates the enhanced acute-phase response and … ginger coiffeur winterthur
KLF4-dependent phenotypic modulation of smooth …
WebJan 13, 2013 · We identified large numbers of phenotypically modulated SMCs in lesions that showed no detectible expression of MYH11 ( Fig. 4c) or ACTA2 ( Fig. 4d) and were identifiable as being of SMC origin... WebOct 7, 2024 · To form the FC, SMC undergo phenotypic modulation in response to atherogenic stimuli and migrate from the media into atherosclerotic lesions. 5–7 Recent lineage tracing studies in mice revealed that SMC can be beneficial or detrimental in atherosclerotic lesions, depending on the specific SMC phenotypic transitions. 7–13 For … WebJun 26, 2008 · Animal Model KLF5 is a transcription factor for Smemb/nonmuscle myosin heavy chain B, which is a molecular marker of phenotypically modulated smooth muscle cells. Normally, KLF5 is abundantly expressed in developing blood vessels, but is downregulated in adult vessels. ginger cold tolerance